Cardiac CaMKIIδ and Wenxin Keli Prevents Ang II-Induced Cardiomyocyte Hypertrophy by Modulating CnA-NFATc4 and Inflammatory Signaling Pathways in H9c2 Cells
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منابع مشابه
SOCS3 is involved in cardiomyocyte hypertrophy induced by Ang II
This study is to explore the effects of two Suppressors of Cytokine Signalling (SOCS) members, namely SOCS-1 and -3, on the regulation of cardiomyocyte hypertrophic response induced by Angiotensin-2 (AngII). Rat neonatal cardiomyocytes culture were cultured and treated with Angiotensin II. After SOCS1 and SOCS3 inhibition by si-RNA transfection, the cellular hypertrophic response indicated by c...
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We investigated the effects of Wenxin Keli (WXKL) on the Calcium/Calmodulin dependent kinase II (CaMK II) signal transduction pathway with transverse aortic constriction (TAC) rats. Echocardiographic measurements were obtained 3 and 9 weeks after the surgery. Meanwhile, the action potentials (APDs) were recorded using the whole-cell patch clamp technique, and western blotting was used to assess...
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ژورنال
عنوان ژورنال: Evidence-Based Complementary and Alternative Medicine
سال: 2020
ISSN: 1741-4288,1741-427X
DOI: 10.1155/2020/9502651